Comparative Study of Prostatic Diseases Bph and Prostatic Cancer by Estimating Serum Pap and Total Psa Levels
نویسنده
چکیده
Objective: To compare prostatic diseases like BPH and Prostatic cancer by estimating the levels of serum Prostatic Acid phosphatase (PAP) and total PSA levels. PSA is an extremely useful tumour marker in prostatic diseases. In normal cases PSA ranges from 0-4ng/ml. Values between 4-10ng/ml are seen in cases of BPH and above levels are seen in prostatic cancer. Normal serum PAP ranges from 0-5 K.A units/dl. Elevated levels can be seen in benign conditions like BPH and also in malignant conditions like prostate cancer with and without metastasis. Total PSA levels were estimated by ELISA and serum PAP levels were estimated by K.A method. Results: In our present study, significant elevation (p<0.001) of PSA was observed in malignant tumours with >20ng/dl and in BPH around 10ng/ml. Serum PAP levels were elevated in cases of BPH and prostatic cancer. Conclusion: Significant elevation of total PSA in BPH cases and cancer of the prostate with and without metastasis.
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